Fun with FGF21

...Did everyone just panic-buy an FGF21?

Oct 14

18

3

September 2025

How Amgen Lost The PCSK9 Patent War

In 2014, Amgen sued Sanofi and Regeneron to claim ownership of an entire class of cholesterol drugs. Nine years later, the Supreme Court ruled against…

Sep 25 • 

Alex Kesin

16

2

August 2025

The Cowboy Of Generic Drugs

A review of Yossi Goldstein's "Eli Hurvitz and the Creation of Teva Pharmaceuticals"

Aug 22 • 

Alex Kesin

18

2

The Day Novartis Chose Discovery

How a Swiss pharma giant built the last great corporate research skunkworks - and why that model may never work again.

Aug 5 • 

Alex Kesin

66

3

July 2025

July in Israel

The Iran thing canceled my June trip, which was fine because I’d been drilling Hebrew conjugations since January anyway, rolling those impossible…

Jul 25 • 

Alex Kesin

4

June 2025

The Hollow Men of Hims

An admittedly partial–but deeply troubling–case against America's most brazen medical grift, involving Chinese knockoffs, subscription traps, and…

Jun 25 • 

Alex Kesin

330

23

Against "Against Life Extension"

A response to Francis Fukuyama's case against longevity research

Jun 4 • 

Alex Kesin

20

Biotech Life in the Software City

What it's like living as someone working in biotech in San Francisco.

Jun 2 • 

Alex Kesin

27

2

May 2025

Still Here, Still Jewish

May 22 • 

Alex Kesin

2

Mr. Secretary, Reclassify the Statin

One regulatory stroke could save more American lives than a decade of health campaigns. You have the pen.

May 15 • 

Alex Kesin

41

11

Playing Poker With Marty Makary

Populism, policy, and poker: Makary’s volatile hand at the FDA

May 7 • 

Alex Kesin

5

1

April 2025

The Pageant of Responsible Longevity

On the quiet horror of healthspan science and its desperate decorum

Apr 26 • 

Alex Kesin

5

2